First Month Free On Select Products!

drawer icon
profile-icon

Sign In

cart-no-item

Men's Hair Loss

Men's Sexual Health

Women's Hair Loss

treatment image

Men's Hair Loss

messages icon

Certified prescriptions

messages icon

Fast, online telehealth visits

messages icon

Over 1 million patients served

product image

2:1 Sildenafil + Tadalafil Blend

2-in-1 ED Treatment: Combines the active ingredients in Viagra® and Cialis® (Sildenafil + Tadalafil)
  • Fast-Acting: Effective in as soon as 15 minutes
  • Long-Lasting: Remains active for up to 36 hours
  • Quick Performance: Works 4x faster than Sildenafil alone
  • Affordable: Starting at $7 per lozenge

Important information

drawer icon

Disclaimer: All BosleyRx prescription orders are processed as one-time shipments by default. If you would like to enroll in automatic shipments, you may select this option at checkout or anytime through the BosleyRx Patient Portal. Patients who choose automatic refills can receive their prescriptions every 3, 6, or 12 months after the initial order. Before each shipment, you will receive a notification. You may cancel or adjust your auto-shipments at any time through the Patient Portal or by calling BosleyRx Patient Services at (877) 352-1906.

product image

Don't delay, start now!

Important Patient Information

Important Safety Information:
  • Purpose: Treats erectile dysfunction (ED) with compounded prescription drugs sildenafil and tadalafil
  • Regulation: Compounded drugs are permitted by federal law but are not FDA-approved and do not undergo FDA safety, effectiveness, or manufacturing review.
  • Dosage: Do not take more than once in any 24-hour period or within 24 hours of other ED medications or PDE-5 inhibitors.

Warnings:
  • Avoid if taking nitrates or soluble guanylate cyclase stimulators, as this can cause a dangerous drop in blood pressure.
  • Do not use if you are not healthy enough for sex.
  • Seek emergency medical care if an erection lasts longer than four hours.
  • Use caution with alpha-blockers, high blood pressure medications, or if consuming more than five units of alcohol.
  • Seek immediate medical attention for sudden loss of vision in one or both eyes, or sudden decrease or loss of hearing.
  • Common Side Effects: Headache, flushing, indigestion, abnormal vision, back pain, muscle pain, nasal congestion, dizziness, nausea, limb pain, and rash.

Citations:
Cui H, Liu B, Song Z, Fang J, Deng Y, Zhang S, Wang H, Wang Z. Efficacy and safety of long-term tadalafil 5 mg once daily combined with sildenafil 50 mg as needed at the early stage of treatment for patients with erectile dysfunction. Andrologia. 2015 Feb;47(1):20-4. doi: 10.1111/and.12216. Epub 2014 Jan 6. PMID: 24387078.
Fink HA, Mac Donald R, Rutks IR, Nelson DB, Wilt TJ. Sildenafil for male erectile dysfunction: a systematic review and meta-analysis. Arch Intern Med. 2002 Jun 24;162(12):1349-60. doi: 10.1001/archinte.162.12.1349. PMID: 12076233.
Gong B, Ma M, Xie W, Yang X, Huang Y, Sun T, Luo Y, Huang J. Direct comparison of tadalafil with sildenafil for the treatment of erectile dysfunction: a systematic review and meta-analysis. Int Urol Nephrol. 2017 Oct;49(10):1731-1740. doi: 10.1007/s11255-017-1644-5. Epub 2017 Jul 24. PMID: 28741090; PMCID: PMC5603624.

Disclaimer:

Cialis® is a registered trademark of Lilly ICOS LLC. Viagra® is a registered trademark of Pfizer, Inc. All other trademarks are the property of their respective owners. BosleyRx is a registered trademark of Bosley, Inc.

®Bosley, Inc. 2025

What is Bosley 2:1 Oral Sildenafil + Tadalafil?

  • A long-lasting ED treatment in a new for quicker absorption and more spontaneity
  • Combines the active ingredients of Viagra (sildenafil 60mg) and Cialis (tadalafil 10mg) for a powerful effect
  • Typically, effective within 15-30 minutes, lasting up to 24 hours
  • Consult now with our licensed medical provider to determine if Bosley 2:1 Sildenafil + Tadalafil is suitable for you

How do I take it?

  • For best results: take one capsule orally, 30 minutes prior to sexual activity on an empty stomach with an 8oz. glass of water.
  • If taking after a meal, for best results take one capsule orally 1-4 hours prior to sexual activity.

Tip: Test the treatment alone first to understand your body’s response

What are common side effects?

  • Mild side effects: headaches, nasal congestion, flushing, dizziness, and upset stomach
  • Rare but serious side effects: low blood pressure and priapism (prolonged erection lasting more than four hours). Seek immediate medical attention if either occur
  • Do not exceed the prescribed amount and do not take more than once in 24 hours, or within 24 hours of other ED medications or PDE-5 inhibitors